Management of Avian Influenza H9N2 Vaccination in Broiler Chickens at JAPFA COMFEED Myanmar Pte Ltd.

Authors

Bagas Ridjalu Verian
Doctor of Veterinary Medicine Program, Faculty of Veterinary Medicine, Universitas Brawijaya, Malang, Indonesia
Dodik Prasetyo
Faculty of Veterinary Medicine Universitas Brawijaya, Malang, Indonesia
Sruti Listra Adrenalin
Faculty of Veterinary Medicine Universitas Brawijaya, Malang, Indonesia
Dyah Kinasih Wuragil
Faculty of Veterinary Medicine Universitas Brawijaya, Malang, Indonesia
Budi Nur Cahyo
JAPFA COMFEED Myanmar Pte Ltd

Page: 16-22, Abstract views: 98, PDF downloads: 90

DOI:

https://doi.org/10.21776/ub.VetBioClinJ.2024.006.01.3

Keywords:

Avian Influenza, Broiler chicken, H9N2

Abstract

Avian influenza virus subtype H9N2 (AIV-H9N2) has been a concern for poultry health in the last 20 years. The virus emerged in domestic poultry in the mid-1990s and has been reported in several Asian countries, including Myanmar. AI subtype H9N2 caused huge economic losses to the poultry industry in the form of respiratory distress and 25% weight loss in broiler chickens. This study discusses the administration of Avian Influenza (AI) H9N2 strain inactivated vaccine to commercial broiler chickens at JAPFA COMFEED Myanmar Pte Ltd. The vaccination process was carried out through subcutaneous injection in the neck and intramuscular injection in the pectoralis musculus in the chest area of chickens at 11 days of age, with a dose of 0.5 ml per chicken. The vaccine used was VAKSIMUNE® AI H9 which uses oil as the emulsion material. Results from the HI serology test showed that 6 cages from Myothar and Wah Net Chaung farms showed protective antibody titers against Avian Influenza H9N2 virus at 30-40 days of age, with normal titer values or ≥24. This indicates that the AI subtype H9N2vaccine used is an effective antigen, capable of stimulating the broiler immune system, and has implications for increasing antibodies every week. This study contributes to the understanding of AI H9N2 vaccination management in commercial broilers at JAPFA COMFEED Myanmar Pte Ltd. With positive results in the serology test, it can be concluded that vaccination using VAKSIMUNE® AI H9 is effective in protecting broilers from Avian Influenza H9N2 infection, providing strong support to the sustainability of production and animal health in a commercial farm environment.


References

  • Abdel, H. H. S., Ellakany, H. F., Hussien, H. A., El-Bestawy, A. R., & Abdel, K. M. (2016). Pathogenicity of an Avian Influenza H9N2 Virus isolated From Broiler Chickens in Egypt. Alexandria Journal of Veterinary Sciences, 51(2), 90–100. https://doi.org/10.5455/ajvs.236275
  • Aiyer, H. P., Ashok, K. H. G., Kumar, G. P., & Neeta, S. (2012). An Overview of Immunologic Adjuvants - A Review. Journal of Vaccines & Vaccination, 04(01), 1000167. https://doi.org/10.4172/2157-7560.1000167
  • Al-Garib, S., Agha, A., & Al-Mesilaty, L. (2016). Low pathogenic avian influenza H9N2: worldwide distribution. World’s Poultry Science Journal, 72(1), 125–136. https://doi.org/10.1017/S0043933915002603
  • Bakhtiar. (2011). Manifestasi Klinis, Tatalaksana dan Pencegahan Avian Influenza pada Anak. Jurnal Kedokteran Syiah Kuala, 11(1), 16–27.
  • Bano, S., Naeem, K., & Malik, S. A. (2003). Evaluation of Pathogenic Potential of Avian Influenza Virus Serotype H9N2 in Chickens. Avian Diseases, 47(s3), 817–822. https://doi.org/10.1637/0005-208647.s3.817
  • Elfidasari, D., Puspitasari, R. L., & Frisa, A. (2014). Deteksi Antibodi Akibat Paparan Virus AI Subtipe H5N1 pada Unggas Air Domestik di Sekitar Cagar Alam Pulau Dua. Jurnal Al-Azhar Indonesia Seri Sains Dan Teknologi, 2(4), 260–269. https://doi.org/10.36722/sst.v2i4.162
  • Fusaro, A., Monne, I., Salviato, A., Valastro, V., Schivo, A., Amarin, N. M., Gonzalez, C., Ismail, M. M., Al Ankari, A.-R., Al-Blowi, M. H., Khan, O. A., Maken Ali, A. S., Hedayati, A., Garcia Garcia, J., Ziay, G. M., Shoushtari, A., Al Qahtani, K. N., Capua, I., Holmes, E. C., & Cattoli, G. (2011). Phylogeography and Evolutionary History of Reassortant H9N2 Viruses with Potential Human Health Implications. Journal of Virology, 85(16), 8413–8421. https://doi.org/10.1128/JVI.00219-11
  • Helmi, T. Z., Tabbu, C. R., Artama, W. T., Haryanto, A., & Isa, M. (2016). Isolation and Identification of Avian Influenza in Different Species of Poultry by Means of Serological and Molecular Methods. Jurnal Kedokteran Hewan - Indonesian Journal of Veterinary Sciences, 10(1), 86–90. https://doi.org/10.21157/j.ked.hewan.v10i1.3378
  • Indriani, R., Dharmayanti, N. L. P. I., & Adjid, R. M. A. (2011). Tingkat proteksi beberapa vaksin Avian Influenza unggas terhadap infeksi virus isolat lapang A/chicken/West Java/Smi-Pat/2006 dan A/chicken/West Java/Smi-Mae/2008 pada Kondisi Laboratorium. JITV, 16(2), 153–161.
  • Kapczynski, D. R., Afonso, C. L., & Miller, P. J. (2013). Immune responses of poultry to Newcastle disease virus. Developmental & Comparative Immunology, 41(3), 447–453. https://doi.org/10.1016/j.dci.2013.04.012
  • Kencana, G. A. Y., Suartha, I. N., Paramita, N. M. A. S., & Handayani, A. N. (2016). Combined Newcastle Disease and Avian Influenza Vaccines Induce Protective Immune Response In Commercial Layer Against Newcastle Disease and Avian Influenza. Jurnal Veteriner, 17(2), 257–264. https://doi.org/10.19087/jveteriner.2016.17.2.257
  • Kim, H. R., Lee, Y. J., Park, C. K., Oem, J. K., Lee, O.-S., KAng, H. M., Choi, J. G., & Bae, Y. C. (2012). Highly Pathogenic Avian Influenza (H5N1) Outbreaks in Wild Birds and Poultry, South Korea. Emerging Infectious Diseases, 18(3), 480–483. https://doi.org/10.3201/eid1803.111490
  • Mahardika, I. G. N. K., Astawa, I. N. M., Kencana, G. A. Y., Suardana, I. B. K., & Sari, T. K. (2016). Teknik Lab Virus. Udayana University Press.
  • Nili, H., & Asasi, K. (2002). Natural cases and an experimental study of H9N2 avian influenza in commercial broiler chickens of Iran. Avian Pathology, 31(3), 247–252. https://doi.org/10.1080/03079450220136567
  • Palese, P., & Shaw, M. L. (2007). Fields virology. Orthomyxoviridae: The Viruses and Their Replication (5th ed.). PA: Lippincott Williams & Wilkins, Wolters Kluwer Business.
  • Plotkin, J. B., Dushoff, J., & Levin, S. A. (2002). Hemagglutinin sequence clusters and the antigenic evolution of influenza A virus. Proceedings of the National Academy of Sciences, 99(9), 6263–6268. https://doi.org/10.1073/pnas.082110799
  • Pusch, E. A., & Suarez, D. L. (2018). The Multifaceted Zoonotic Risk of H9N2 Avian Influenza. Veterinary Sciences, 5(4), 82. https://doi.org/10.3390/vetsci5040082
  • Putri, D. D., Chandra, A. A., & Zairiful. (2012). The Best Timing ofAvian Influenza (AI) Vaccination to Give Immun Protective Respons forBroile. Jurnal Penelitian Pertanian Terapan, 12(3), 150–155.
  • Shankar, B. P., Gowda, R. N. S., Manjunath, B. H., Pattnaik, B., Nagarajan, S., Patil, S. S., & Pradhan, H. K. (2009). Assessment of Pathogenic Potential of Two Indian H5N1 Highly Pathogenic Avian Influenza Virus Isolates by Intravenous Pathogenicity Index Test. International Journal of Poultry Science, 8(3), 283–290. https://doi.org/10.3923/ijps.2009.283.290
  • Siegist, C. A., & Lambert, P. H. (2016). The Vaccine Book: Chapter 2 How Vaccine Work. Elsevier Inc.
  • Tabbu, C. R. (2000). Penyakit Ayam dan Penanggulangannya. . Penerbit Kanisius.
  • Thuy, D. M., Peacock, T. P., Bich, V. T. N., Fabrizio, T., Hoang, D. N., Tho, N. D., Diep, N. T., Nguyen, M., Hoa, L. N. M., Trang, H. T. T., Choisy, M., Inui, K., Newman, S., Trung, N. vu, van Doorn, R., To, T. L., Iqbal, M., & Bryant, J. E. (2016). Prevalence and diversity of H9N2 avian influenza in chickens of Northern Vietnam, 2014. Infection, Genetics and Evolution, 44, 530–540. https://doi.org/10.1016/j.meegid.2016.06.038
  • Tizard. (1982). Imunology Veteriner. Saunders Company.
  • WHO (World Health Organization). (2017). Epidemiological and virological updates on influenza circulation.
  • Yusdja, Y., Basuno, E., & Ilham, N. (2010). Dampak Wabah Avian Influenza dan Usaha Pengendaliannya terhadap Sosial-Ekonomi Peternak Unggas Skala Kecil di Indonesia. Bogor

Downloads

Download data is not yet available.

Downloads


Published

2024-06-30

How to Cite

Verian, B. R., Prasetyo, D., Adrenalin, S. L., Wuragil, D. K., & Cahyo, B. N. (2024). Management of Avian Influenza H9N2 Vaccination in Broiler Chickens at JAPFA COMFEED Myanmar Pte Ltd. Veterinary Biomedical and Clinical Journal, 6(1), 16–22. https://doi.org/10.21776/ub.VetBioClinJ.2024.006.01.3

Issue


Section

Articles