Antibiotic Sensitivity Profile of Pasteurella multocida in Cattle in Malang, Indonesia
Page: 79-85,
Abstract views: 52,
PDF downloads: 31
DOI:
https://doi.org/10.21776/ub.VetBioClinJ.2024.006.02.4%20%20Keywords:
antibiotic susceptibility, cattle, Indonesia, Malang, pasteurellosisAbstract
This study was conducted in Malang, Indonesia, to assess the prevalence and antibiotic susceptibility of Pasteurella multocida in cattle exhibiting clinical signs of respiratory disease. Nasal and tracheal swabs were collected from 50 cattle across multiple farms and tested for P. multocida. The isolates were identified through colony morphology, Gram staining, and biochemical tests, with 4 out of 50 samples (8%) testing positive for P. multocida. Antibiotic susceptibility was determined using the disk diffusion method, involving seven antibiotics commonly used in veterinary practice. Results showed that 75% of the isolates were sensitive to ceftriaxone, while amoxicillin-clavulanic acid was effective in 50% of cases. However, all isolates demonstrated resistance to erythromycin and tetracycline. These findings emphasize the importance of susceptibility testing to guide appropriate antibiotic therapy and prevent the development of resistance. Further research is necessary to monitor resistance patterns and improve treatment strategies for pasteurellosis in cattle.
References
- Abed, A. H., El-Seedy, F. R., Hassan, H. M., Nabih, A. M., Khalifa, E., Salem, S. E., Wareth, G., & Menshawy, A. M. S. (2020). Serotyping, genotyping and virulence genes characterization of Pasteurella multocida and Mannheimia haemolytica isolates recovered from pneumonic cattle calves in North Upper Egypt. Veterinary Sciences, 7(4), 174. https://doi.org/10.3390/vetsci7040174
- Akhter, S., Zihadi, M. A. H., Rahman, M. H., & Rahman, M. Z. (2023). Multi-drug resistant Mannheimia hemolytica and Pasteurella multocida in pneumonic sheep in Bangladesh. Bangladesh Journal of Infectious Diseases, 10(1), 16-23. https://doi.org/10.3329/bjid.v10i1.68746
- Alemu, S., Belachew, Y., & Tefera, T. (2023). Isolation and molecular detection of Mannheimia haemolytica and Pasteurella multocida from clinically pneumonic pasteurellosis cases of bonga sheep breed and their antibiotic susceptibility tests in selected areas of southwest Ethiopian people regional state, Ethiopia. Veterinary Medicine: Research and Reports, Volume 14, 233-244. https://doi.org/10.2147/vmrr.s435932
- Ara, M. S., Rahman, M. T., Akhtar, M., Rahman, M., Nazir, K. H. M. N. H., Ahmed, S., Hossen, M. L., Khan, M. F. R., & Rahman, M. B. (2016). Molecular detection of Pasteurella multocida Type B causing haemorrhagic septicaemia in cattle and buffaloes of Bangladesh. Progressive Agriculture, 27(2), 175-179. https://doi.org/10.47278/journal.ijvs/2023.016
- Besung, I. N. K., Ketut Tono, P. G., Tenden Rompis, A. L., & Suarjana, I. G. K. (2016). Prevalensi Pasteurella multocida pada sapi Bali di Bali (Prevalence of Pasteurella multocida in Bali cattle in Bali). Buletin Veteriner Udayana, 8(2), 145–150.
- Clinical and Laboratory Standards Institute. (2020). Performance standards for antimicrobial susceptibility testing (M100, 30th ed.). CLSI. https://clsi.org/standards/
- Desem, M. I., Handharyani, E., Setiyono, A., Safika, S., Subekti, D. T., & Ekawasti, F. (2023). Morphology, biochemical, and molecular characterization of Pasteurella multocida causing hemorrhagic septicemia in Indonesia. Veterinary Medicine International, 2023, 7778707. https://doi.org/10.1155/2023/7778707
- Gharibi, D., Hajikolaei, M. R. H., Ghorbanpour, M., & Barzegar, S. K. (2017). Virulence gene profiles of Pasteurella multocida strains isolated from cattle and buffalo. Veterinarski Arhiv, 87(6), 677-690. https://doi.org/10.24099/vet.arhiv.160727
- Hasnan, Q., Puspitasari, Y., Othman, S., Zamri-Saad, M., & Salleh, A. (2022). Phagocytosis and intracellular killing of Pasteurella multocida B:2 by macrophages: A comparative study between buffalo and cattle. Veterinary World, 15(2), 275-280. https://doi.org/10.14202/vetworld.2022.275-280
- Mushtaq, H. A., Rafique, R., Naveed, M. A., Anjum, A., Ali, S., Tania, H. A., Arfat, M. Y., Naeem, M., Fraz, A., Abdullah, M., Khan, M. N., Huma, I., & Shahid, S. (2023). Molecular characterization, antibiotic susceptibility and biofilm forming ability of Pasteurella multocida isolated from the respiratory microbiota of healthy bovines. Pakistan Journal of Science, 75(3), September 2023. https://doi.org/10.57041/pjs.v75i03.994
- Qandoos, A. Z., Ahmed, H., & El-Ghany, W. A. A. (2022). The in-vitro antibiotic sensitivity test of Pasteurella multocida isolated from layer and breeder chickens. Journal of World’s Poultry Science, 1(1), 12-15. https://doi.org/10.58803/jwps.v1i1.2
- Sayed, R. H., Elsaady, S. A., Shasha, F. A., Abousenna, M. S., Mahmoud, H., Soliman, H. M., & Amal, A. M. (2023). Diagnosis of Pasteurella multocida and Mannheimia haemolytica infections in cattle using lateral flow immunochromatographic assay. International Journal of Veterinary Science, 22(784), 1–. https://doi.org/10.47278/journal.ijvs/2023.019.
- Venu, G., Krishna, S. V., & Jyothi, J. S. (2023). Antibiogram study of Pasteurella multocida strains isolated from pneumonic sheep and goats in Warangal region of Telangana. International Journal of Veterinary Sciences and Animal Husbandry, 8(5), 85-87. https://doi.org/10.22271/veterinary.2023.v8.i5b.692.
- Vu-Khac, H., Trinh, T. T. H., Nguyen, T. T. G., Nguyen, X. T., & Nguyen, T. T. (2020). Prevalence of virulence factor, antibiotic resistance, and serotype genes of Pasteurella multocida strains isolated from pigs in Vietnam. Veterinary World, 13(5), 896-904. https://doi.org/10.14202/vetworld.2020.896-904.
- Wang, Z., Kong, L.-C., Jia, B.-Y., Liu, S.-M., Jiang, X.-Y., & Ma, H.-X. (2017). Aminoglycoside susceptibility of Pasteurella multocida isolates from bovine respiratory infections in China and mutations in ribosomal protein S5 associated with high-level induced spectinomycin resistance. Journal of Veterinary Medical Science, 79(10), 1678-1681. https://doi.org/10.1292/jvms.17-0219.
Downloads
Download data is not yet available.
Downloads
Published
2024-12-31
How to Cite
Dodik Prasetyo, Amri, I. A., Dian Siswanto, Rahayu Shafa Camila Sanjoyo, Monica Widyaningrum, Tanti Widya, & Fidi Nur Eka Puji Dameanti. (2024). Antibiotic Sensitivity Profile of Pasteurella multocida in Cattle in Malang, Indonesia. Veterinary Biomedical and Clinical Journal, 6(2), 79–85. https://doi.org/10.21776/ub.VetBioClinJ.2024.006.02.4
License
Copyright (c) 2024 Dodik Prasetyo, Indah Amalia Amri, Dian Siswanto, Rahayu Shafa Camila Sanjoyo, Monica Widyaningrum, Tanti Widya, Fidi Nur Eka Puji Dameanti
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Most read articles by the same author(s)
- Eka Wulandari, Indah Amalia Amri, Identification of Colibacillosis and Antibiotic Resistance Test in Free-range Chicken , Veterinary Biomedical and Clinical Journal: Vol. 4 No. 1 (2022)
- Bian Febry Rohmana Alviano, Indah Amalia Amri, Effect of Oregano (Origanum vulgare) Extract on Kidney Histomorphometry and Histopathology in Mice (Mus musculus) Colibacillosis Model , Veterinary Biomedical and Clinical Journal: Vol. 5 No. 1 (2023)
